Gregory VERT - Ubiquitin-mediated regulation of cell signaling and endocytosis in plant
Plant Science Research Laboratory of Toulouse
Mardi 10 février, 11h00Passat
Ubiquitination is a post-translational modification essential for the regulation of eukaryotic proteins, having an impact on protein fate, function, localization or activity. What originally appeared to be a simple system to regulate protein turnover by the 265 proteasome is now known to be the most intricate regulatory process cells have evolved.
Ubiquitin can be arranged in countless chain assemblies, and here I will present our work deconstructing lysine(K)63-linked polyubiquitin chains using plants as model and highlighting its major contribution in the control of plasma membrane protein dynamics.
