Guest speakers: Maria MOTA, Florian SCHMIDT, Ana-Maria LENNON DUMENIL

Day 1 - November 21

09.00 Opening and welcome, Dr. Olivier NEYROLLES, Director of IPBS

INFECTIOUS DISEASES

(Chairs, Drs. Thomas BENOIST and Caio BOMFIM)
09.10 Dr. Maria MOTA, Institute of Molecular Medicine, University of Lisbon, Portugal
Plasmodium liver stage: silently making a bang
10.10 Second-year PhD student flash presentations - Session 1
10.20 Sponsor presentation
10.35 Poster session 1 and Coffee break
11.20 Léa FROMONT – Unraveling the dynamics of T lymphocytes in the lung during Mycobacterium tuberculosis infection
11.35 Maxime CAOUAILLE – Unraveling CD8+ T cell diversity: New insights into tuberculosis immunity and disease severity
11.50 Natacha FAIVRE – Understanding macrophage polarization and metabolic shifts: a perspective in HIV-1/M. tuberculosis co-infection?
12.05: Yasmine HAMCHAOUI – The FAS-II system: An anti-tuberculosis therapeutic target
12.20 Lunch

PROTEIN STRUCTURE and FUNCTION

(Chairs, Drs. Angélique DAFUN and Albertus VILJOEN)
13.50 Maxime NORIEGA – Understanding signal transduction by the Mincle receptor
14.05 Louis BÉNASTRE – Biochemical and structural study of a zinc efflux pump implicated in the adaptation of M. tuberculosis within infected macrophages
14.20 Pauline LIZONDO-BALDERAS – Engineering, biophysical and structural characterization of new Jo-In complexes for the design of artificial cellulosomes
14.35 Ronald SIADEN-ORTEGA – In Pore-suit of antimicrobial peptide dynamics and oligomerization within bacterial membranes
14.50 Floriane AUDEBERT– Development of conformation antibodies targeting the Nociceptin receptor (NOR) involved in pain and inflammation: production of functional NOR in bicelles
15.05 Second-year PhD student flash presentations - Session 2
15.15 Poster session 2 and Coffee break

REGULATION of INFLAMMATION

(Chairs, Drs. Henrich GASPAROVIC and Saurabh CHUGH)
16.05 Dr. Florian SCHMIDT, Institute of Innate Immunity, University Hospital Bonn, Germany
Interrogating infection and immunity with camelid nanobodies
17.05 Stella ROUSSET – Targeting the C-type lectin receptor DCIR using single-domain antibodies: a novel strategy for immunomodulation in tuberculosis
17.20 Léana GORSE – Portimine A toxin causes skin pathology through ZAK-alpha-dependent NLRP1 inflammasome activation
17.35 Bastien SUIRE – Impact of Kaftrio treatment on infection by Mycobacterum abscessus in cystic fibrosis patients
17.50 End of the day

Day 2 - November 22

IMMUNITY and CANCER (Sponsored by Fondation Toulouse Cancer Santé)

(Chairs, Drs. Pauline SCHMITT and Javier REY-BARROSO)
09.05 Océane DEWINGLE – Detection of nanotopographies by macrophages
09.20 Marianna PLOZZA – Integrin regulation in osteoclast formation and function: a potential target to prevent tumor-induced bone loss?
09.35 Dr. Ana-Maria LENNON DUMENIL, Institut Curie, Paris, France
How the nucleus of Dendritic Cells defines their immune sentinel function
10.35 Poster session 3 and Coffee Break
11.20 Hector MAYORAL-REYES – Enhancing autophagy to improve immune response to BCG
11.35 Carl KHAWLY – Small GTPases in lung cancer: A functional and structural study of the new RhoB-Ral interaction
11.50 Closing remarks and poster prizes
12.15 End of the symposium