Dezember 2025

Dienstag 2
- 15:00 - 16:00

CBI Toulouse - Salle de conférence IBCG

169 Rue Marianne Grunberg-Manago, 31400 Toulouse

Haute-Garonne

Occitanie

Arnaud Gutierrez “Progress in Antibiotic Persistence: We Found the Needle in the Haystack”

Name: Arnaud Gutierrez “Progress in Antibiotic Persistence: We Found the Needle in the Haystack”
Start: 2025-12-02T15:00:00+01:00
End: 2025-12-02T16:00:00+01:00
Location: CBI Toulouse - Salle de conférence IBCG

Institut Cochin, Paris

Dienstag 2 Dezember 2025, 15:00

Passed

Infectious diseases remain a major public health challenge, exacerbated by the rise of resistance to antimicrobial treatments. The overall goal of this project is to identify new genetic and physiological determinants to better understand therapeutic failures associated with bacterial infections. This work focuses on the mechanisms underlying bacterial survival and adaptation to lethal stresses, particularly those induced by antibiotics and bacteriophages. By combining approaches from genetics, molecular biology, and microfluidics, we explore the links between metabolism and bactericidal activity to elucidate the phenomena of tolerance and persistence. We also aim to understand how environmental structuring influences the resilience of bacterial populations to antibiotics and bacteriophages. Finally, we investigate how the selective pressure exerted by certain bacteriophages can promote the emergence of antibiotic resistance. Together, these studies contribute to a deeper understanding of microbial adaptive dynamics and pave the way for new therapeutic strategies to combat antimicrobial resistance.

Dezember 2025

Dienstag 2
- 15:00 - 16:00

Additionnal information

Type d'évènements

CBI Public Seminar

Über den Standort

CBI Toulouse - Salle de conférence IBCG

169 Rue Marianne Grunberg-Manago, 31400 Toulouse

Haute-Garonne

Occitanie

Comprendre le fonctionnement des organismes vivants, telle est l’ambition du Centre de biologie intégrative (CBI), à Toulouse. Pour atteindre cet objectif, le CBI développe des approches multidisciplinaires, multi-échelles des molécules isolées aux organismes entiers et aux sociétés animales, et utilise de nombreux organismes modèles, des bactéries à l'homme.

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